Malavefes : A computational voice-enabled malaria fuzzy informatics software for correct dosage prescription of anti-malarial drugs

The use of anti-malarial drugs to prevent malaria in the population of malaria-endemic areas.

Anti-malarial drugs have been used in various ways to prevent malaria in the resident populations of endemic areas for nearly 100 years. The primary aim of most early studies was to interrupt transmission. This was rarely achieved, but administration of anti-malarial drugs either through medication of salt or by mass administration frequently led to a marked reduction in the prevalence of malar...

Improving the correct prescription and dosage of gentamicin

Gentamicin is an amino glycoside antibiotic, which is used predominantly in gram-negative infections but also has anti-staphylococcal activity. It is commonly used because of its lack of diffogenicity. There are recognised issues with its dosing of which time is a major factor. A baseline study demonstrated that dosing was only being carried out correctly 30% of the time. This has serious conse...

The history of anti-malarial drugs.

anti-malarial discovery from plant sources: chemo-informatics approach

Computational screening of molecular targets in Plasmodium for novel non resistant anti-malarial drugs

Histone acetyltransferase (HAT) is an enzyme required for chromatin remodeling and transcriptional activation. Sarcoendoplasmic reticulum Ca(2+) ATPase (SERCA) is an ATP coupled Ca(2+) ion pump involved in metabolic arrest. Both these enzymes are present in Plasmodia and have been selected as molecular targets for in silico studies of some new non-resistant antimalarial drugs like artemisinin, ...